Vioxx Research - Osteoarthritis, Side-effects, Trials, Stroke, Heart Attack

Vioxx Research Today is a free monthly online journal that collates and summarizes the latest research about Vioxx, including details on osteoarthritis, side-effects, trials, stroke, heart attack.


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Volume 3 (2006), Issue 12 (December)

  1. Simultaneous assessment of short-term gastrointestinal benefits and cardiovascular risks of selective cyclooxygenase 2 inhibitors and nonselective nonsteroidal antiinflammatory drugs: an instrumental variable analysis.
    Arthritis Rheum, 54(11): 3390-8. [Abstract] [Full-text]
  2. Healing Impairment Effect of Cyclooxygenase Inhibitors on Dextran Sulfate Sodium-Induced Colitis in Rats.
    Digestion, 74(2): 91-100. [Abstract] [Full-text]
  3. Stronger inhibition by nonsteroid anti-inflammatory drugs of cyclooxygenase-1 in endothelial cells than platelets offers an explanation for increased risk of thrombotic events.
    FASEB J, 20(14): 2468-75. [Abstract] [Full-text]
  4. Mucosal acid causes gastric mucosal microcirculatory disturbance in nonsteroidal anti-inflammatory drug-treated rats.
    Eur J Pharmacol, 554(1): 53-9. [Abstract] [Full-text]
  5. Studies on dissolution enhancement and mathematical modeling of drug release of a poorly water-soluble drug using water-soluble carriers.
    Eur J Pharm Biopharm, 65(1): 26-38. [Abstract] [Full-text]
  6. Immunohistochemical measurement of endothelial cell apoptosis and proliferation in formalin-fixed, paraffin-embedded human cancer tissue.
    Angiogenesis, 9(4): 193-200. [Abstract] [Full-text]
  7. Methodological shortcomings predicted lower harm estimates in one of two sets of studies of clinical interventions.
    J Clin Epidemiol, 60(1): 18-28. [Abstract] [Full-text]
  8. Chemoprevention of colorectal cancer: two steps forward, one step back?
    Future Oncol, 2(6): 697-704. [Abstract] [Full-text]
  9. Pharmacodynamic of cyclooxygenase inhibitors in humans.
    Prostaglandins Other Lipid Mediat, 82(1): 85-94. [Abstract] [Full-text]
  10. Synthesis and biological evaluation of methanesulfonamide analogues of rofecoxib: Replacement of methanesulfonyl by methanesulfonamido decreases cyclooxygenase-2 selectivity.
    Bioorg Med Chem, 15(2): 1056-61. [Abstract] [Full-text]
  11. Structure-based pharmacophore of COX-2 selective inhibitors and identification of original lead compounds from 3D database searching method.
    Eur J Med Chem, 41(12): 1446-55. [Abstract] [Full-text]
  12. Do selective COX-2 inhibitors increase the risk of cerebrovascular events? A meta-analysis of randomized controlled trials.
    J Clin Pharm Ther, 31(6): 565-76. [Abstract] [Full-text]
  13. Licofelone, a balanced inhibitor of cyclooxygenase and 5-lipoxygenase, reduces inflammation in a rabbit model of atherosclerosis.
    J Pharmacol Exp Ther, 320(1): 108-16. [Abstract] [Full-text]
  14. Inflammation-induced reduction of spontaneous activity by adjuvant: A novel model to study the effect of analgesics in rats.
    J Pharmacol Exp Ther, 320(1): 194-201. [Abstract] [Full-text]
  15. Rofecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor potentiates the anticonvulsant activity of tiagabine against pentylenetetrazol-induced convulsions in mice.
    Inflammopharmacology, 14(5): 222-5. [Abstract] [Full-text]
  16. Selective cyclooxygenase-2 inhibitors stimulate glucose transport in L6 myotubes in a protein kinase Cdelta-dependent manner.
    Biochem Pharmacol, 73(3): 368-77. [Abstract] [Full-text]
  17. A randomized trial of rofecoxib for the chemoprevention of colorectal adenomas.
    Gastroenterology, 131(6): 1674-82. [Abstract] [Full-text]
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Vioxx Research Today Archive:

Volume 1 (2004)
  Issue 1 (November)
  Issue 2 (December)

Volume 2 (2005)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 3 (2006)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 4 (2007)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 5 (2008)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 6 (2009)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 7 (2010)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 8 (2011)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 9 (2012)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 10 (2013)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 11 (2014)
  Issue 1 (January)
  Issue 2 (February)



Vioxx Books

Pain in Osteoarthritis

Pain in Osteoarthritis